Developed and produced by Shandong Camasy Biotechnology Co. Ltd, DEFATA is a sucrose polyester covalent with eight fatty acid residues and eight active hydroxyls. Compared with other kinds of sucrose polyester, in addition to the effect of absorption of intestinal fatty substance, DEFATA has advantages of not being hydrolyzed and destroyed by hepatic lipase and pancreatic lipase in the intestinal tract, with no side effects. Therefore, no matter taking alone, or being used as fat substitute, DEFATA has a significant effect of cleaning fat.
Sucrose polyester is a fat substitute that does not contain fat and cholesterol. It has been used in the preparation of high-fat foods such as potato chips and frito to lower or eliminate fat absorption after consumption.
Mechanism of action
In human gastrointestinal tract, the digestive enzymes digesting fatty substance mainly includes hepatic lipase secreted from the liver and pancreatic lipase secreted from the pancreas. These two categories of esterase hydrolyze fatty substance intaked from food into all kinds of fatty acids and glycerol, which will then be absorbed by intestine into the body needs energy and matter, while the fatty acids which has not become energy will be transformed into triglycerides and stored as fat in the fat cell. This is one of the main reasons why people get fat. Sucrose polyester is a kind of special molecular structure, which has effect of affinity interation with free fatty acid and more carbon chain triglyceride, thus can adsorp fatty substance in the gut, no matter use alone or as fat substitute, it has significant effect in cleaning intestinal fat and promoting fat into energy.
The history of sucrose polyester can be traced back to the 1960’s which is reported that sucrose polyester can effectively reduce the human body cholesterol levels and effectively reduce the risk of cancer. The Food and Drug Administration (“FDA”) permitted olestra (a sucrose polyester produced by P&G) using as a substitute of fats and oils in prepackaged ready-to-eat snacks in 1996, concluded that such use "meets the safety standard for food additives, reasonable certainty of no harm". Since then sucrose polyester has been widely applied in the high-calorie and high-fat foods production.